Tramiprosate, a drug of potential interest for the treatment of Alzheimer's disease, promotes an abnormal aggregation of tau

@article{SantaMara2007TramiprosateAD,
  title={Tramiprosate, a drug of potential interest for the treatment of Alzheimer's disease, promotes an abnormal aggregation of tau},
  author={Ismael Santa-Mar{\'i}a and Felix Hernandez and J R Send{\'o}n del R{\'i}o and F Javier Moreno and Jes{\'u}s {\'A}vila},
  journal={Molecular Neurodegeneration},
  year={2007},
  volume={2},
  pages={17 - 17}
}
Alzheimer's disease (AD) is characterized by the presence of two histopathological hallmarks; the senile plaques, or extracellular deposits mainly composed of amyloid-β peptide (Aβ), and the neurofibrillary tangles, or intraneuronal inclusions composed of hyperphosphorylated tau protein. Since Aβ aggregates are found in the pathological cases, several strategies are under way to develop drugs that interact with Aβ to reduce its assembly. One of them is 3-amino-1-propane sulfonic acid… CONTINUE READING
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Clinical data on Alzhemed after 12 months of treatment in patients with mild to moderate Alzheimer's disease

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  • Neurobiology of Aging
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