Trametes robiniophila may induce apoptosis and inhibit MMPs expression in the human gastric carcinoma cell line MKN-45.
@article{Ji2017TrametesRM, title={Trametes robiniophila may induce apoptosis and inhibit MMPs expression in the human gastric carcinoma cell line MKN-45.}, author={Xuening Ji and Chunxia Pan and X. Li and Yunbin Gao and L. Xia and Xiulian Quan and Jinyan Lv and R. Wang}, journal={Oncology letters}, year={2017}, volume={13 2}, pages={ 841-846 } }
Gastric carcinoma (GC) is one of the most common malignant tumors and is mainly treated by invasive surgeries. The present study aimed to investigate the treatment potential of Trametes robiniophila on GC using the human GC cell line MKN-45. Cells were incubated with Trametes robiniophila at a concentration of 0, 5 and 10 mg/ml for 24 h. The apoptosis of the cell line was examined with acridine orange/ethidium bromide staining and flow cytometry. The expression of B-cell lymphoma (Bcl)-2, Fas… CONTINUE READING
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