Tramadol as an adjunct to intra‐articular local anaesthetic infiltration in knee arthroscopy: a systematic review and meta‐analysis

  title={Tramadol as an adjunct to intra‐articular local anaesthetic infiltration in knee arthroscopy: a systematic review and meta‐analysis},
  author={Thomas Ryan and Anthony Hodge and Rhys S. Holyoak and Ruan Vlok and Thomas Melhuish and Matthew Binks and Glenn Hurtado and Leigh White},
  journal={ANZ Journal of Surgery},
Arthroscopic knee surgery is a common technique used in Australia. Post‐operative pain is common and can lead to delayed discharge and impair early mobilization. Use of local anaesthesia can reduce pain while avoiding systemic side effects. This systematic review and meta‐analysis aimed to establish the use of tramadol as an adjunct to intra‐articular local anaesthetic infiltration in knee arthroscopy in the current literature. 
3 Citations
Do intra-articular injections of analgesics improve outcomes after temporomandibular joint arthrocentesis? : A systematic review and meta-analysis.
Low quality evidence suggests that intra-articular NSAIDs may have no effect on pain and MMO after TMJ arthrocentesis, while intra-Articular opioids may improve pain andORPG at short term follow-up.
Peri- and Postoperative Pain Management in Multiple Ligament Knee Surgery in the Hospital and Ambulatory Surgery Center Setting.
An outline of the types of pain most often sustained in the multiligament knee injury is provided, the phases of pain management are outlined, and an overview of persistent postoperative pain is provided.
Acute Pseudogout Attack Precipitated by Intra-Articular Injection of a Cross-Linked Hyaluronate Combined with Triamcinolone Hexacetonide
A patient who developed acute pseudogout after IA Cingal injection is reported, despite the triamcinolone hexacetonide given in the IA, and previous reports were reviewed and discussed preventive and management approaches to avoid such an unpleasant but, thankfully, a rare occurrence.


Intraarticular Tramadol-Bupivacaine Combination Prolongs the Duration of Postoperative Analgesia After Outpatient Arthroscopic Knee Surgery
The IA admixture of tramadol 100 mg with bupivacaine 0.25% provides a pronounced prolongation of analgesia compared with either drug alone in patients undergoing day care arthroscopic knee surgery.
Comparison of the Efficacy of Intra-Articular Bupivacaine with Intra-Articular Admixture of Bupivacaine and Tramadol in the Immediate Postop Management of Pain after knee Arthroscopy
Intraarticular admixture of 100 mg tramadol with 0.5% bupvacaine decreased both visual analogue pain scale and provided longer postoperative analgesia than that produced by intraarticular injection of either bupivacaine alone.
Preemptive intraarticular tramadol for pain control after arthroscopic knee surgery.
  • B. Tuncer, A. Babacan, M. Arslan
  • Medicine
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology
  • 2007
Adjuncts to local anaesthetics in tonsillectomy: a systematic review and meta-analysis
This systematic review of RCTs provides strong evidence that the use of dexamethasone and magnesium as additives to local anaesthetics reduces post-tonsillectomy pain and analgesia requirement.
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This study suggests that tramadol added to 1.5% mepivacaine for brachial plexus block enhances in a dose-dependent manner the duration of analgesia with acceptable side effects, however, the safety of tramadols has to be investigated before allowing its use in clinical practice.
Bupivacaine/ketamine is superior to intra-articu-lar ketamine analgesia following arthroscopic knee surgery
It is concluded that intra-articular bupivacaine-ket-amine combination provides better pain relief than intra-artsicu-lar ketamine after day care arthroscopic knee surgery.
The comparison effects of intra-articular injection of different opioids on postoperative pain relieve after arthroscopic anterior cruciate ligament reconstruction: A randomized clinical trial study*
Administering 5 mg intra-articular morphine after arthroscopic ACL reconstruction is a valuable choice and is recommended to be added to other local anesthetics administrated drugs after this procedure.
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It is concluded that the most effective drugs that are administered intraarticularly are neostigmine and clonidine among the five drugs that were studied in 150 patients undergoing arthroscopic knee surgery.