Trajectory events across hippocampal place-cells require previous experience

@inproceedings{Silva2015TrajectoryEA,
  title={Trajectory events across hippocampal place-cells require previous experience},
  author={Delia Silva and Ting Feng and D. J. Foster},
  booktitle={Nature Neuroscience},
  year={2015}
}
Replay of hippocampal place cell sequences has been proposed as a fundamental mechanism of learning and memory. However, the standard interpretation of replay has been challenged by reports that similar activity is observed before experience ('preplay'). By the preplay account, pre-existing temporal sequences are mapped onto new experiences without learning sequential structure. Here we employed high density recording methods to monitor hundreds of place cells simultaneously while rats explored… CONTINUE READING

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