Traitement des douleurs post-zostériennes par le tramadol

  title={Traitement des douleurs post-zost{\'e}riennes par le tramadol},
  author={Horst G{\"o}bel and T. Stadler},
English AbstractTo date, no universally applicable recommendations are available for the treatment of patients with postherpetic neuralgia. A mixture of clinical anecdotes, experimental findings and observations from clinical trials form the basis of the medical arsenal for this condition. Tricyclic antidepressants are commonly used, and clinical experience and several investigations have documented their effectiveness.Today, single entity antidepressants, which can be combined with… 
Gabapentin for the management of intractable postherpetic neuralgia: Report of 4 cases
The measurements of pain as well as mood status, sleep and activity showed improvement with a high degree of satisfaction and without significant adverse effects in all four patients during Gabapentin treatment at the daily dose of 600-900 mg.
Discovery and development of tramadol for the treatment of pain
The combination of monoamine and opioid mechanisms opens new avenues for the design of innovative analgesic drugs to treat moderate to severe pain.
Revisiting Tramadol: A Multi-Modal Agent for Pain Management
Given the broad spectrum of molecular targets, tramadol as a unimodal analgesic relieves a broad range of pain types, such as postoperative, low back, and neuropathic pain and that associated with labor, osteoarthritis, fibromyalgia, and cancer.
Managing Chronic Non-Malignant Pain in the Elderly: Intrathecal Therapy
Current knowledge regarding intrathecal opioid therapy is reviewed, focusing particularly on the use of IDD in elderly patients, and the arguments in favor of and against this therapy in elderly Patients are discussed.
Antipsychotics for acute and chronic pain in adults.
Use of antidepressants in dentistry: A systematic review.
There is rationality for the indication of this class of medicine in dentistry in specific clinical situations, but there is a large amount of methodological heterogeneity among the evaluated studies.
Neuropathic Pain and Other Chronic Musculoskeletal Pain Conditions
The objective of this chapter is to review the pathophysiology and treatment approach in various chronic pain conditions, such as neuropathic pain and other chronic musculoskeletal pain conditions.
Opioide bei chronischen nicht-tumorbedingten Schmerzen – sind sie Nichtopioidanalgetika überlegen?
ZusammenfassungHintergrundManche Meinungsbildner in der deutschen Schmerzmedizin vertreten die These, dass es chronische nicht-tumorbedingte opioidpflichtige Schmerzen (CNTS) gibt. In der
Atypical Analgesics


Orale Opiattherapie bei Patienten mit “nicht-malignen” Schmerzen
The results show that patients with musculo-skeletal and deafferentation pain respond better to opioids than patients with headache and that opioids are justifiable for the treatment of non-malignant pain and can be given without danger over a long period of time.
Desipramine relieves postherpetic neuralgia.
It is concluded that desipramine administration relieves postherpetic neuralgia and that pain relief is not mediated by mood elevation, and blockade of norepinephrine reuptake, an action shared by desIPramine, amitriptyline, and other antidepressant agents that have relieved neuropathic pain, may be involved in relief of postherPetic Neuralgia.
Amitriptyline, but not lorazepam, relieves postherpetic neuralgia
Greater relief was associated with higher amitriptyline doses, up to the maxiumum dose of 150 mg/d, and with higher serum tricyclic levels, and in four patients with postherpetic neuralgia.
The future for antidepressants: treatment of pain.
  • R. France
  • Psychology, Medicine
  • 1987
Data presented in this paper suggest that antidepressant drugs may be effective in the treatment of postherpetic neuralgia, back pain, and pain from mixed etiologies; however, data for these pain syndromes are less clear, and, thus, further testing is required.
A randomized, within‐patient, cross‐over, placebo‐controlled trial on the efficacy and tolerability of the tricyclic antidepressants chlorimipramine and nortriptyline in central pain
A randomized, within‐patient (cross‐over) placebo‐controlled study in patients suffering from central pain indicates the better analgesic effect of tricyclic antidepressants over placebo and the antinociceptive effect is independent of the effects of the two drugs on the symptoms of depression.
Complementary and synergistic antinociceptive interaction between the enantiomers of tramadol.
A rational explanation for the coexistence of dual components to tramadol-induced antinociception appears to be related to the different, but complementary and interactive, pharmacologies of its enantiomers and might form the basis for understanding its clinical profile.