Trailmaking and number-connection tests in the assessment of mental state in portal systemic encephalopathy

@article{Conn1977TrailmakingAN,
  title={Trailmaking and number-connection tests in the assessment of mental state in portal systemic encephalopathy},
  author={Harold O. Conn},
  journal={The American Journal of Digestive Diseases},
  year={1977},
  volume={22},
  pages={541-550}
}
  • H. Conn
  • Published 1 June 1977
  • Psychology
  • The American Journal of Digestive Diseases
The quanti tat ive assessment of mental state is a difficult and imprecise art. Simple, reliable tests for quantifying the degree of portal systemic or other types of encephalopathy are not readily available. It is cus tomary in clinical pract ice to assess mental state in the course of a casual conversa t ion or by a series of perfunctory questions ( " W h a t is the da t e?" or " W h o is the pres ident?") . Although these " t e s t s " are simple and permit differentiating confused patients… 

Diagnosis of minimal hepatic encephalopathy: still a challenge

Hepatic encephalopathy (HE) describes the spectrum of potentially reversible neuropsychiatric abnormalities seen in patients with liver dysfunction after exclusion of unrelated neurological and/or

The study of psychometric test for detection and assessment in subclinical hepatic encephalopathy

For quick assessment of mental status and screening for detecting SHE in cases of cirrhosis of liver with portal hypertension, TMT test is useful and for complete assessment of cerebral function derangement WAPIS is most sensitive and complete test.

Standardization of the psychometric hepatic encephalopathy score in a French population

This is the first study to standardize the PHES in a French population and to extensively explore the effects of sex, age and education using perfectly balanced samples.

EVALUATION OF CRITICAL FLICKER FREQUENCY IN DETECTING AND MONITORING MINIMAL HEPATIC ENCEPHALOPATHY

Critical Flicker Frequency measurement is a simple and reliable tool for detection of MHE and has high degree of reproducibility & lack of learning effect on repeated testing in the same patient.

Study on the Sternberg Paradigm in Cirrhotic Patients Without Overt Hepatic Encephalopathy

Cirrhotics without over encephalopathy, but with NCT or EEG alterations, perform a computerized digit recognition task more slowly and with higher TOs than cirrhotic patients with normal NCT orEEG alterations.

Diagnostic tools for the detection of subclinical hepatic encephalopathy: comparison of standard and computerized psychometric tests with spectral-EEG

Neurophysiological and neuropsychological impairment in cirrhotics without overt hepatic encephalopathy were found linked to each other and to hepatic dysfunction; psychometric tests were not sufficiently good predictors of EEG alterations; therefore, neuropsychology tools can not substitute neurophysiological ones to detect CNS dysfunction in liver disease.

Towards Chronic Liver Dysfunction Self-monitoring: a Proof-of-Concept Study

A proof-of-concept study aimed at detecting ammonia in the breath of patients suffering from chronic liver disease by means of a low-cost, easy-to-use, gas-sensors based device and investigating the possibility of discriminating the several severity degree of liver impairment on the basis of the detected ammonia.

Extrapyramidal signs predict the development of overt hepatic encephalopathy in patients with liver cirrhosis

The presence of extrapyramidal signs in patients with liver cirrhosis predicts the development of overt hepatic encephalopathy (HE) and these signs increased along the follow-up, and remain a bad influence on quality of life.
...

References

SHOWING 1-10 OF 29 REFERENCES

Correlations between the Trail Making Test and the Wechsler-Bellevue Scale

The present study was designed to determine the degree of correlation among scores on the Trail Making Test and various scores from the Wechsler-Bellevue Scale, Form I.

Method for Measuring Cerebral Dysfunction in Patients with Liver Disease

Objective tests of cerebral function were undertaken in 64 outpatients after portal decompression for intrahepatic portal hypertension, and a simple modification of the Reitan trail making test was found to be less discriminating than the second.

The syndrome of impending hepatic coma in patients with cirrhosis of the liver given certain nitrogenous substances.

The diagnosis of impending hepatic coma has been clarified by the clinical observations of Adams and Foley, who described mental disturbances and a characteristic tremor before the onset of the comatose state.

The measurement of ammonia in whole blood, erythrocytes, and plasma.

The ammonia found in freshly drawn human venous blood is believed to be preformed true ammonia, present as ammonium ions and not an artifact.

Pathogenesis and treatment of hepatic failure.

  • T. Chalmers
  • Medicine
    The New England journal of medicine
  • 1960
It is said in summary that abnormalities in the metabolism of ammonia have been found to be linked to Hepatic Coma in men and women with high serum ammonia levels.

Partington's Pathways Test.

Validity of the Trail Making Test as an Indicator of Organic Brain Damage