Trafficking of Sendai Virus Nucleocapsids Is Mediated by Intracellular Vesicles

@inproceedings{Chambers2010TraffickingOS,
  title={Trafficking of Sendai Virus Nucleocapsids Is Mediated by Intracellular Vesicles},
  author={Raychel Chambers and Toru Takimoto},
  booktitle={PloS one},
  year={2010}
}
BACKGROUND Paramyxoviruses are assembled at the plasma membrane budding sites after synthesis of all the structural components in the cytoplasm. Although viral ribonuclocapsid (vRNP) is an essential component of infectious virions, the process of vRNP translocation to assembly sites is poorly understood. METHODOLOGY/PRINCIPAL FINDINGS To analyze real-time trafficking of vRNPs in live infected cells, we created a recombinant Sendai virus (SeV), rSeVLeGFP, which expresses L protein fused to… CONTINUE READING