Traditional serrated adenoma has two pathways of neoplastic progression that are distinct from the sessile serrated pathway of colorectal carcinogenesis

@article{Tsai2014TraditionalSA,
  title={Traditional serrated adenoma has two pathways of neoplastic progression that are distinct from the sessile serrated pathway of colorectal carcinogenesis},
  author={J H Tsai and Jau-Yu Liau and Yu-lin Lin and Liang-In Lin and Y. Cheng and Mei-Ling Cheng and Yung-Ming Jeng},
  journal={Modern Pathology},
  year={2014},
  volume={27},
  pages={1375-1385}
}
Traditional serrated adenoma is one type of colorectal serrated neoplasm and a precursor of colorectal cancer. We evaluated the pathologic and molecular features of 60 traditional serrated adenomas with cytologic dysplasia and/or invasive carcinoma. On the basis of morphological features, 16 cases (27%) were categorized as traditional serrated adenoma with serrated dysplasia and 25 cases (42%) as traditional serrated adenoma with conventional adenomatous dysplasia. In addition, 19 cases (31… CONTINUE READING
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