Tractography in amyotrophic lateral sclerosis using a novel probabilistic tool: a study with tract-based reconstruction compared to voxel-based approach.

@article{Sarica2014TractographyIA,
  title={Tractography in amyotrophic lateral sclerosis using a novel probabilistic tool: a study with tract-based reconstruction compared to voxel-based approach.},
  author={Alessia Sarica and Antonio Cerasa and Roberta Vasta and Paolo Perrotta and Paola Valentino and Graziella Mangone and Pietro Hiram Guzzi and Federico Rocca and Matteo Nonnis and Mario Cannataro and Aldo Quattrone},
  journal={Journal of neuroscience methods},
  year={2014},
  volume={224},
  pages={79-87}
}
BACKGROUND Diffusion tensor imaging (DTI) is one of the most sensitive MRI tools for detecting subtle cerebral white matter abnormalities in amyotrophic lateral sclerosis (ALS). Nowadays a plethora of DTI tools have been proposed, but very few methods have been translated into clinical practice. NEW METHOD The aim of this study is to validate the objective measurement of fiber tracts as provided by a new unbiased and automated tractography reconstruction tool named as TRActs Constrained by… CONTINUE READING