Tracking the roots of cellulase hyperproduction by the fungus Trichoderma reesei using massively parallel DNA sequencing.

@article{Crom2009TrackingTR,
  title={Tracking the roots of cellulase hyperproduction by the fungus Trichoderma reesei using massively parallel DNA sequencing.},
  author={St{\'e}phane Le Crom and Wendy S. Schackwitz and Len A. Pennacchio and Jon Karl Magnuson and David E. Culley and James R. Collett and Joel Martin and Irina S Druzhinina and H. Mathis and Fr{\'e}d{\'e}ric Monot and Bernhard Seiboth and Barbara Cherry and Michael Rey and Randy Berka and Christian Peter Kubicek and Scott E Baker and Antoine Margeot},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2009},
  volume={106 38},
  pages={16151-6}
}
Trichoderma reesei (teleomorph Hypocrea jecorina) is the main industrial source of cellulases and hemicellulases harnessed for the hydrolysis of biomass to simple sugars, which can then be converted to biofuels such as ethanol and other chemicals. The highly productive strains in use today were generated by classical mutagenesis. To learn how cellulase production was improved by these techniques, we performed massively parallel sequencing to identify mutations in the genomes of two… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 80 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 37 references

A complex of Shc and Ran-GTPase localises to the cell nucleus

  • R George
  • Cell Mol Life Sci 66:711–720
  • 2009

Similar Papers

Loading similar papers…