Tracking the ends: a dynamic protein network controls the fate of microtubule tips

@article{Akhmanova2008TrackingTE,
  title={Tracking the ends: a dynamic protein network controls the fate of microtubule tips},
  author={A. Akhmanova and M. Steinmetz},
  journal={Nature Reviews Molecular Cell Biology},
  year={2008},
  volume={9},
  pages={309-322}
}
Microtubule plus-end tracking proteins (+TIPs) are a diverse group of evolutionarily conserved cellular factors that accumulate at the ends of growing microtubules. They form dynamic networks through the interaction of a limited set of protein modules, repeat sequences and linear motifs that bind to each other with moderate affinities. +TIPs regulate different aspects of cell architecture by controlling microtubule dynamics, microtubule interactions with cellular structures and signalling… Expand
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