Tracking the Evolution of Polymerase Genes of Influenza A Viruses during Interspecies Transmission between Avian and Swine Hosts

@inproceedings{Karnbunchob2016TrackingTE,
  title={Tracking the Evolution of Polymerase Genes of Influenza A Viruses during Interspecies Transmission between Avian and Swine Hosts},
  author={Nipawit Karnbunchob and Ryosuke Omori and Heidi L. Tessmer and Kimihito Ito},
  booktitle={Front. Microbiol.},
  year={2016}
}
Human influenza pandemics have historically been caused by reassortant influenza A viruses using genes from human and avian viruses. This genetic reassortment between human and avian viruses has been known to occur in swine during viral circulation, as swine are capable of circulating both avian and human viruses. Therefore, avian-to-swine transmission of viruses plays an important role in the emergence of new pandemic strains. The amino acids at several positions on PB2, PB1, and PA are known… CONTINUE READING
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