Tracking microbial colonization in fecal microbiota transplantation experiments via genome-resolved metagenomics

@inproceedings{Lee2017TrackingMC,
  title={Tracking microbial colonization in fecal microbiota transplantation experiments via genome-resolved metagenomics},
  author={Sonny T M Lee and Stacy A. Kahn and Tom O. Delmont and Alon Shaiber and {\"O}zcan C. Esen and Nathaniel A. Hubert and Hilary G. Morrison and Dionysios A. Antonopoulos and David T Rubin and A. Murat Eren},
  booktitle={Microbiome},
  year={2017}
}
BACKGROUND Fecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridium difficile infection and shows promise for treating other medical conditions associated with intestinal dysbioses. However, we lack a sufficient understanding of which microbial populations successfully colonize the recipient gut, and the widely used approaches to study the microbial ecology of FMT experiments fail to provide enough resolution to identify populations that are likely responsible… CONTINUE READING