Tracking genomic instability within irradiated and bystander populations.

  title={Tracking genomic instability within irradiated and bystander populations.},
  author={Kim L Chapman and James William Kelly and Ryonfa Lee and Edwin H. Goodwin and Munira A. Kadhim},
  journal={The Journal of pharmacy and pharmacology},
  volume={60 8},
Over the past two decades, our understanding of radiation biology has undergone a fundamental shift in paradigms away from deterministic 'hit-effect' relationships and towards complex ongoing 'cellular responses'. These responses include now familiar, but still poorly understood, phenomena associated with radiation exposure such as genomic instability and bystander effects. Although these responses share some common features (e.g. they occur at high frequency following very low doses, are… CONTINUE READING