Tracing the route of modern humans out of Africa by using 225 human genome sequences from Ethiopians and Egyptians.

@article{Pagani2015TracingTR,
  title={Tracing the route of modern humans out of Africa by using 225 human genome sequences from Ethiopians and Egyptians.},
  author={Luca Pagani and Stephan Schiffels and Deepti Gurdasani and Petr Danecek and Aylwyn Scally and Yuan Xiu Chen and Yali Xue and Marc Haber and Rosemary Ekong and Tamiru Oljira and Ephrem Mekonnen and Donata Luiselli and Neil N Bradman and Endashaw J. Bekele and Pierre A. Zalloua and Richard Durbin and Toomas Kivisild and Chris Tyler-Smith},
  journal={American journal of human genetics},
  year={2015},
  volume={96 6},
  pages={986-91}
}
The predominantly African origin of all modern human populations is well established, but the route taken out of Africa is still unclear. Two alternative routes, via Egypt and Sinai or across the Bab el Mandeb strait into Arabia, have traditionally been proposed as feasible gateways in light of geographic, paleoclimatic, archaeological, and genetic evidence. Distinguishing among these alternatives has been difficult. We generated 225 whole-genome sequences (225 at 8× depth, of which 8 were… CONTINUE READING

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