Trace detection of specific viable bacteria using tetracysteine-tagged bacteriophages.

@article{Wu2014TraceDO,
  title={Trace detection of specific viable bacteria using tetracysteine-tagged bacteriophages.},
  author={Lina Wu and Tian Luan and Xiaoting Yang and Shuo Wang and Yan Zheng and Tianxun Huang and Shaobin Zhu and Xiaomei Yan},
  journal={Analytical chemistry},
  year={2014},
  volume={86 1},
  pages={
          907-12
        }
}
Advanced methods are urgently needed to determine the identity and viability of trace amounts of pathogenic bacteria in a short time. Existing approaches either fall short in the accurate assessment of microbial viability or lack specificity in bacterial identification. Bacteriophages (or phages for short) are viruses that exclusively infect bacterial host cells with high specificity. As phages infect and replicate only in living bacterial hosts, here we exploit the strategy of using… CONTINUE READING