Trace MicroRNA Quantification by Means of Plasmon-Enhanced Hybridization Chain Reaction.


Quantifying trace microRNAs (miRNAs) is extremely important in a number of biomedical applications but remains a great challenge. Here we present an enzyme-free amplification strategy called plasmon-enhanced hybridization chain reaction (PE-HCR) for quantifying trace miRNAs with an outstanding linear range from 1 fM to 1 pM (r(2) = 0.991), along with a… (More)
DOI: 10.1021/acs.analchem.6b00772


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