Trabecular bone response to mechanical and parathyroid hormone stimulation: the role of mechanical microenvironment.

@article{Kim2003TrabecularBR,
  title={Trabecular bone response to mechanical and parathyroid hormone stimulation: the role of mechanical microenvironment.},
  author={Chi Hyun Kim and E Lima Takai and Hua Zhou and Dietrich von Stechow and Ralph M{\"u}ller and David W. Dempster and Xiangdong Edward Guo},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={2003},
  volume={18 12},
  pages={2116-25}
}
UNLABELLED Bone response under combined mechanical and PTH stimuli is important in osteoporosis. A rat tail animal model with computer modeling was used to examine bone response to loading and PTH. PTH enhances and sustains increased bone formation rate, which directly correlates to mechanical microenvironment, suggesting beneficial effects of combined PTH treatment and exercise in preventing osteoporosis. INTRODUCTION Using an in vivo rat tail vertebra model combined with a specimen-specific… CONTINUE READING
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