Toxoplasma gondii rhoptry discharge correlates with activation of the early growth response 2 host cell transcription factor.

@article{Phelps2008ToxoplasmaGR,
  title={Toxoplasma gondii rhoptry discharge correlates with activation of the early growth response 2 host cell transcription factor.},
  author={Eric D Phelps and Kristin R Sweeney and Ira J. Blader},
  journal={Infection and immunity},
  year={2008},
  volume={76 10},
  pages={4703-12}
}
Toxoplasma gondii is a ubiquitous apicomplexan parasite that can cause severe disease in fetuses and immune-compromised patients. Rhoptries, micronemes, and dense granules, which are secretory organelles unique to Toxoplasma and other apicomplexan parasites, play critical roles in parasite growth and virulence. To understand how these organelles modulate infected host cells, we sought to identify host cell transcription factors triggered by their release. Early growth response 2 (EGR2) is a… CONTINUE READING
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