Toxoplasma gondii infection lower anxiety as measured in the plus-maze and social interaction tests in rats A behavioral analysis

 Toxoplasma gondii infection lower anxiety as measured in the plus-maze and social interaction tests in rats A behavioral analysis},
  author={Luis E. Gonzalez and Belen Rojnik and Franklin Urrea and Hayd{\'e}e Urdaneta and Pierina Petrosino and Cesare Colasante and Silvano Pino and Luis Hern{\'a}ndez},
  journal={Behavioural Brain Research},
Infection of male rats with Toxoplasma gondii results in enhanced delay aversion and neural changes in the nucleus accumbens core
It is shown that infection with T. gondii increases the propensity of the infected rats to make more impulsive choices, manifested as delay aversion in an intertemporal choice task, which is consistent with a role of the nucleus accumbens dopaminergic system in mediation of choice impulsivity and goal-directed behaviours.
Toxoplasma gondii Infection in Mice Impairs Long-Term Fear Memory Consolidation through Dysfunction of the Cortex and Amygdala
Examination of memory associated with conditioned fear in mice found that T. gondii infection impairs consolidation of conditioned fear memory through dysfunction of the cortex and amygdala, providing insight into the mechanisms underlying the neurological changes seen during T. Gondii infections.
Effects of Toxoplasma gondii infection on anxiety, depression and ghrelin level in male rats
It seems that latent T. gondii infection decreases the ghrelin serum level but does not change anxiety and depression like behaviors, and here there were no significant correlations between gh Relin level and anxiety or depression in rats.
Impaired social behaviour and molecular mediators of associated neural circuits during chronic Toxoplasma gondii infection in female mice
It is shown that infection leads to an impairment in neuronal activation in the medial prefrontal cortex, hippocampus as well as the amygdala when mice are exposed to a social environment and a change in functional connectivity between these regions.


Effect of Toxoplasma gondii upon neophobic behaviour in wild brown rats, Rattus norvegicus.
It is suggested that differences between infected and uninfected wild rats arise from pathological changes caused by Toxoplasma cysts in the brains of infected rats, which may render T Oxoplasma-infected rats more susceptible to predation by domestic cats and, as a side-effect, more vulnerable to trapping and poisoning during post control programmes.
Behavioral alterations caused by parasitic infection in case of latent toxoplasma infection.
  • G. Piekarski
  • Biology, Medicine
    Zentralblatt fur Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie = International journal of microbiology and hygiene. A, Medical microbiology, infectious...
  • 1981
Fatal attraction in rats infected with Toxoplasma gondii
Although rats have evolved anti–predator avoidance of areas with signs of cat presence, T. gondii's manipulation appears to alter the rat's perception of cat predation risk, in some cases turning their innate aversion into an imprudent attraction.
The effect of congenital and adult-acquired Toxoplasma infections on activity and responsiveness to novel stimulation in mice.
Differences arise from pathological changes caused by proliferating toxoplasms in the brains of the infected mice; an immunopathological reaction due to the presence of tissue cysts in the brain may also be involved.
Chronic Toxoplasma infections and familiarity-novelty discrimination in the mouse.
If Toxoplasma infections impair responsiveness to novel stimuli, then infected mice are more likely to be taken by predators, and this suggestion has important implications for the understanding of one of the major ways in which T oxoplasma passes from host to host.
The effect of Toxoplasma gondii and other parasites on activity levels in wild and hybrid Rattus norvegicus.
This study shows that the indirect life-cycle parasite T. gondii can influence the activity of its intermediate host the rat, and suggests that this may facilitate its transmission to the cat definitive host.
Sex differences in animal tests of anxiety