Toxoplasma gondii effectors are master regulators of the inflammatory response.

@article{Melo2011ToxoplasmaGE,
  title={Toxoplasma gondii effectors are master regulators of the inflammatory response.},
  author={Mariane B Melo and Kirk D C Jensen and Jeroen P J Saeij},
  journal={Trends in parasitology},
  year={2011},
  volume={27 11},
  pages={487-95}
}
Toxoplasma is a highly successful parasite that establishes a life-long chronic infection. To do this, it must carefully regulate immune activation and host cell effector mechanisms. Here we review the latest developments in our understanding of how Toxoplasma counteracts the immune response of the host, and in some cases provokes it, through the use of specific parasite effector proteins. An emerging theme from these discoveries is that Toxoplasma effectors are master regulators of the pro… CONTINUE READING
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