Toxoplasma gondii Antibody Titers and History of Suicide Attempts in Patients With Recurrent Mood Disorders

@article{Arling2009ToxoplasmaGA,
  title={Toxoplasma gondii Antibody Titers and History of Suicide Attempts in Patients With Recurrent Mood Disorders},
  author={Timothy A Arling and Robert H. Yolken and Manana Lapidus and Patricia W. Langenberg and Faith B Dickerson and Sarah A Zimmerman and Theodora G Balis and Johanna A. Cabassa and Debra A. Scrandis and Leonardo H Tonelli and Teodor Τ Postolache,},
  journal={The Journal of Nervous and Mental Disease},
  year={2009},
  volume={197},
  pages={905-908}
}
Toxoplasma gondii (T.gondii) is an obligate intracellular protozoan parasite infecting one-third of the world population, residing relatively silently in the brain of the immunocompetent host. We hypothesized that T.gondii seropositivity and serointensity are associated with having a history of attempting suicide and, in those attempting suicide, a greater number of attempts. T.gondii seropositivity and antibody titers were compared between (a) patients with recurrent mood disorders with… Expand
Toxoplasma gondii antibody titers and history of suicide attempts in patients with schizophrenia
TLDR
Toxoplasma gondii serology might become, with interaction with vulnerability genes, a candidate biomarker for a subgroup of schizophrenia patients prone to attempting suicide in patients diagnosed with schizophrenia by SCID. Expand
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  • Medicine
  • Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology
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A significant association between T. gondii infection and psychiatric problems in suicidality is suggested and suicide attempters showed higher seroprevalence of T. Gondii than healthy controls. Expand
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TLDR
These data are consistent with previous studies suggesting a relationship between T. gondii and self-directed aggression and further add to the biological complexity of impulsive aggression both from a categorical and a dimensional perspective. Expand
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  • Medicine
  • Archives of suicide research : official journal of the International Academy for Suicide Research
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Toxoplasmosis titers may quantify a proneness to suicidal behavior in younger individuals being treated with antidepressants in younger adolescents who had recently begun treatment with an SSRI. Expand
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No evidence was found for a relationship between affective disorders and T. gondii infection in the current sample, and no significant associations were found between T. gondii seropositivity and disorder status, aggression reactivity and suicidal thoughts. Expand
Association of Suicide Attempt With Seroprevalence of Toxoplasma gondii in Adolescents.
TLDR
Adolescents attempting suicide were found to have worse relationships with their parents; their CDI scores were higher, and their RSES scores were lower than their healthy peers. Expand
Toxoplasma gondii Infection and Suicide Attempts: A Case-Control Study in Psychiatric Outpatients
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The results suggest that although seroprevalence of Toxoplasma infection is not associated with suicide attempts, a high anti-Toxoplasm antibody level is, therefore warranting further research. Expand
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The findings indicate that T. gondii infection is strongly and significantly associated with GAD, and may play a role in the development of GAD. Expand
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It is suggested that a positive relationship between rates of infection with T. gondii and suicide is apparent in women of postmenopausal age, and mechanisms mediating this relationship are explored. Expand
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