Toxoplasma gondii: decreased resistance to infection in mice due to estrogen.

@article{Pung1986ToxoplasmaGD,
  title={Toxoplasma gondii: decreased resistance to infection in mice due to estrogen.},
  author={O J Pung and Michael I. Luster},
  journal={Experimental parasitology},
  year={1986},
  volume={61 1},
  pages={48-56}
}
Exposure to pharmacological concentrations of potent estrogenic compounds, including 17 beta-estradiol, diethylstilbestrol, and alpha-dienestrol, increased the susceptibility of mice to Toxoplasma gondii as measured by brain cyst formation. Compounds with weak estrogenic activity or other hormonal activity, including 5 alpha-dihydrotestosterone, progesterone, and zearalanol, did not alter host resistance to infection. The ability of estrogens to alter susceptibility was inhibited by the… CONTINUE READING