Toxins, Targets, and Triggers: An Overview of Toxin-Antitoxin Biology.

@article{Harms2018ToxinsTA,
  title={Toxins, Targets, and Triggers: An Overview of Toxin-Antitoxin Biology.},
  author={Alexander Harms and Ditlev Egeskov Brodersen and Namiko Mitarai and Kenn Gerdes},
  journal={Molecular cell},
  year={2018},
  volume={70 5},
  pages={
          768-784
        }
}
Bacterial toxin-antitoxin (TA) modules are abundant genetic elements that encode a toxin protein capable of inhibiting cell growth and an antitoxin that counteracts the toxin. The majority of toxins are enzymes that interfere with translation or DNA replication, but a wide variety of molecular activities and cellular targets have been described. Antitoxins are proteins or RNAs that often control their cognate toxins through direct interactions and, in conjunction with other signaling elements… CONTINUE READING