Toxin detection using a tyrosinase-coupled oxygen electrode.

  title={Toxin detection using a tyrosinase-coupled oxygen electrode.},
  author={Maarten Smit and Garry Rechnitz},
  journal={Analytical chemistry},
  volume={65 4},
An enzyme-based "electrochemical canary" is described for the detection of cyanide. The sensing system imitates cyanide's site of toxicity in the mitochondria. The terminal sequence of electron transfer in aerobic respiration is mimicked by mediator coupling of tyrosinase catalysis to an electro-chemical system. An enzyme-coupled oxygen electrode is created… CONTINUE READING