• Medicine
  • Published in
    Journal of the American…
    1993

Toxicoses and efficacy associated with administration of mitoxantrone to cats with malignant tumors.

@article{Ogilvie1993ToxicosesAE,
  title={Toxicoses and efficacy associated with administration of mitoxantrone to cats with malignant tumors.},
  author={Gregory K. Ogilvie and Antony S. Moore and Joyce E. Obradovich and Robyn E. Elmslie and David M. Vail and Rod C. Straw and Mario Dr Ing Salmon and Mary Kay Klein and S W Atwater and P E Ciekot},
  journal={Journal of the American Veterinary Medical Association},
  year={1993},
  volume={202 11},
  pages={
          1839-44
        }
}
Eighty-seven cats with histologically confirmed malignant tumors were used in a prospective study to determine the toxicity of mitoxantrone, a dihydroxyquinone derivative of anthracene, which was administered at 21-day intervals at dosages ranging from 2.5 to 6.5 mg/m2 of body surface, IV. Eleven of these cats were treated concurrently with radiation but were evaluated separately. Each cat was evaluated for signs of toxicosis for 3 weeks after each dose was administered or until the cat… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS