Toxicological significance of DNA adducts: summary of discussions with an expert panel.

@article{Nestmann1996ToxicologicalSO,
  title={Toxicological significance of DNA adducts: summary of discussions with an expert panel.},
  author={Earle R. Nestmann and Douglas W. Bryant and Christopher J. Carr},
  journal={Regulatory toxicology and pharmacology : RTP},
  year={1996},
  volume={24 1 Pt 1},
  pages={9-18}
}
A workshop was held to discuss the uses of data on DNA adduct measurement in humans and in experimental systems in vitro and in vivo. The discussions focused principally on the understanding of the toxicological significance of DNA adducts as provided by information from animal models. An Expert Panel concluded that human DNA adduct data have utility in several aspects of risk assessment. The presence and amount of specific adducts that can be correlated with a chemical exposure are relevant… CONTINUE READING

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