Toxicological investigation of aqueous-methanolic extract of the calyces of Hibiscus sabdariffa L.

@article{Akindahunsi2003ToxicologicalIO,
  title={Toxicological investigation of aqueous-methanolic extract of the calyces of Hibiscus sabdariffa L.},
  author={Afolabi Akintunde Akindahunsi and Mary Tolulope Olaleye},
  journal={Journal of ethnopharmacology},
  year={2003},
  volume={89 1},
  pages={161-4}
}
The aqueous fraction of an aqueous-alcoholic extract of Hibiscus sabdariffa L. calyces was given to Wistar albino rats (150-200g) orally as drugs to study the toxicity of the extract. The rats, which were fed with commercial diet and water ad libitum, were divided into six groups of four rats each. Treatments 1 through 6 received 0, 1, 3, 5, 10 and 15 doses of 250 mg/kg each, respectively; the control group received physiological saline (0.9% NaCl). Results of the studies showed that the levels… CONTINUE READING
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