Toxicological and pharmacological effects of D-arginine.

@article{Navarro2005ToxicologicalAP,
  title={Toxicological and pharmacological effects of D-arginine.},
  author={Eduardo Navarro and S. J. Alonso and Felipe Martı́n and M. A. Castellano},
  journal={Basic \& clinical pharmacology \& toxicology},
  year={2005},
  volume={97 3},
  pages={
          149-54
        }
}
D-Arginine is extensively used in studies on L-arginine/nitric oxide pathway as an inactive form of L-arginine, even in man. In addition, it has previously been reported that this D-amino acid appears to have pharmacological activity. The present work aimed at evaluating the toxicity and pharmacology of D-arginine administered by the intraperitoneally route in albino male mice. Toxicity of D-arginine, alone as well as in the presence of propranolol and betamethasone was evaluated. D-Arginine in… 
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18 Citations
Background Citations
6
Methods Citations
2

18 Citations

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A method for determining the nutritional value of d-amino acids, d-peptides, and amino acid derivatives using a growth assay in mice fed a synthetic all-aminos acid diet is reviewed and interpreted.
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BIOLOGICAL ROLE OF D-α-AMINO ACIDS AND THEIR OCCURENCE IN FOODSTUFFS
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The current understanding of biological and physiological role of D-α-amino acids and the significance of their presence in foodstuffs and the biological role of their D-enantiomers in the body is reviewed.
Article 18.indd
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It is suggested that ethanol extract of E. falcata leaves was able to affect locomotion, exploration, and motivation of animals without anxiolytic/anxiogenic effect, indicating a possible depressant action on the central nervous system.
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