Toxicological and molecular characterization of pyrethroid-resistant horn flies, Haematobia irritans: identification of kdr and super-kdr point mutations.

@article{Guerrero1997ToxicologicalAM,
  title={Toxicological and molecular characterization of pyrethroid-resistant horn flies, Haematobia irritans: identification of kdr and super-kdr point mutations.},
  author={Felix David Guerrero and R C Jamroz and Diane M Kammlah and Sarah Kunz},
  journal={Insect biochemistry and molecular biology},
  year={1997},
  volume={27 8-9},
  pages={745-55}
}
Two pyrethroid-resistant strains of horn flies were found to be 17- and 688-fold more resistant to permethrin and 17- and 11,300-fold more resistant to cyhalothrin than a susceptible control strain. Synergism experiments with piperonyl butoxide showed that both target site insensitivity and metabolic resistance mechanisms were present in the Super Resistant strain. Using the reverse transcriptase-polymerase chain reaction (RT-PCR), a 0.9 kb fragment of the putative sodium channel gene from… CONTINUE READING