Toxicological and gene expression analysis of the impact of aflatoxin B1 on hepatic function of male broiler chicks.

@article{Yarru2009ToxicologicalAG,
  title={Toxicological and gene expression analysis of the impact of aflatoxin B1 on hepatic function of male broiler chicks.},
  author={L P Yarru and Raja S Settivari and Eric Antoniou and David R. Ledoux and George Edwin Rottinghaus},
  journal={Poultry science},
  year={2009},
  volume={88 2},
  pages={360-71}
}
The objective of this study was to determine the effects of dietary aflatoxin B1 (AFB1) on hepatic gene expression in male broiler chicks. Seventy-five 1-d-old male broiler chicks were assigned to 3 dietary treatments (5 replicates of 5 chicks each) from hatch to d 21. The diets contained 0, 1 and 2 mg of AFB1/kg of feed. Aflatoxin B1 reduced (P<0.05) feed intake, BW gain, serum total proteins, and serum Ca and P, but increased (P<0.01) liver weights in a dose-dependent manner. Microarray… CONTINUE READING
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