Toxicokinetics of permethrin in the rat.

  title={Toxicokinetics of permethrin in the rat.},
  author={Arturo Anad{\'o}n and Mar{\'i}a Rosa Mart{\'i}nez-Larra{\~n}aga and Maria Jes{\'u}s Lamas D{\'i}az and Pilar Bringas},
  journal={Toxicology and applied pharmacology},
  volume={110 1},
The toxicokinetics of permethrin after single 460 mg/kg oral and 46 mg/kg intravenous doses were studied in male Sprague-Dawley rats. Serial blood samples after oral and intravenous dosage, and brain, medulla oblongata, sciatic nerve, and liver samples after oral administration were collected. Plasma, hypothalamus, cerebellum, frontal cortex, caudate putamen, hippocampus, medulla oblongata, sciatic nerve, and liver concentrations of permethrin and its metabolites, m-phenoxybenzyl alcohol and m… CONTINUE READING


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