Toxicokinetics of hexavalent chromium in the rat after intratracheal administration of chromates of different solubilities.

@article{Bragt1983ToxicokineticsOH,
  title={Toxicokinetics of hexavalent chromium in the rat after intratracheal administration of chromates of different solubilities.},
  author={Peter C. Bragt and Ernst A van Dura},
  journal={The Annals of occupational hygiene},
  year={1983},
  volume={27 3},
  pages={
          315-22
        }
}
The kinetics of chromium in the rat after a single intratracheal dose of sodium, zinc or lead 51Cr-chromate have been investigated. Sodium chromate and the less soluble zinc chromate were absorbed into the blood and this resulted in increased excretion of chromium into the urine. The insoluble lead chromate was poorly absorbed from the lungs. The more insoluble a chromate was in water, the higher its elimination via the feces. With all three chromates, absorbed chromium was retained in the… CONTINUE READING