Toxicogenomics in risk assessment: applications and needs.

  title={Toxicogenomics in risk assessment: applications and needs.},
  author={D. R. Boverhof and Timothy R. Zacharewski},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  volume={89 2},
Since its inception, there have been high expectations for the science of toxicogenomics to decrease the uncertainties associated with the risk assessment process by providing valuable insights into toxic mechanisms of action. However, the application of these data into risk assessment practices is still in the early stages of development, and proof of principle experiments have yet to emerge. The following discusses some potential applications as well as impediments that warrant a concerted… CONTINUE READING