Toxicogenomic effects of neonatal exposure to diethylstilbestrol on mouse testicular gene expression in the long term: a study using cDNA microarray analysis.

@article{Adachi2002ToxicogenomicEO,
  title={Toxicogenomic effects of neonatal exposure to diethylstilbestrol on mouse testicular gene expression in the long term: a study using cDNA microarray analysis.},
  author={Tetsuya Adachi and Masatoshi Komiyama and Yushin Ono and K Koh and Kenichi Sakurai and Takako Shibayama and Masaki Kato and Tsutomu Yoshikawa and Naohiko Seki and Taisen Iguchi and Chisato Mori},
  journal={Molecular reproduction and development},
  year={2002},
  volume={63 1},
  pages={17-23}
}
We examined the effect of neonatal exposure to diethylstilbestrol (DES) on mouse testicular gene expression, using in-house mouse fetus (day 14.5) cDNA microarrays. Newborn male ICR mice were exposed to DES (50 microg/mouse/day) from neonatal day 1 to 5. Differential expression was detected in 14 genes in 4-week-old (day 28) mouse testes by cDNA microarray analysis; 11 genes (AI035263, AU080565, AU080361, AU080678, AI131681, AU080631, AA986882, AI037066, AA986537, AI156816, and AI596237) were… CONTINUE READING
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