Toxicity of oxygen from naturally occurring redox-active pro-oxidants.

@article{Pardini1995ToxicityOO,
  title={Toxicity of oxygen from naturally occurring redox-active pro-oxidants.},
  author={Ronald S. Pardini},
  journal={Archives of insect biochemistry and physiology},
  year={1995},
  volume={29 2},
  pages={101-18}
}
The survival of all aerobic life forms requires the ground-state of molecular oxygen, O2. However, the activation of O2 to reactive oxygen species (ROS) is responsible for universal toxicity. ROS are responsible in deleterious intracellular reactions associated with oxidative stress including membrane lipid peroxidation, and the oxidation of proteins and DNA. Redox-active allelochemicals such as quinones and phenolic compounds are involved in activating O2 to its deleterious forms including… CONTINUE READING

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