Toxicity of beta-amyloid protein during aging: Influence of synaptosomal energy metabolism

Abstract

Background Recent evidence suggests that early neurodegenerative events associated with Alzheimer’s disease (AD) probably begin in the synaptic terminal, where it has been reported a large accumulation of β-amyloid protein (Aβ), one of the main factors described in the development of AD. We analyzed the influence of energy metabolism on the toxic effects of… (More)

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