Toxicity of Methotrexate Treatment in Psoriasis and Psoriatic Arthritis – Short- and Long-Term Toxicity in 104 Patients

@article{Wollina2001ToxicityOM,
  title={Toxicity of Methotrexate Treatment in Psoriasis and Psoriatic Arthritis – Short- and Long-Term Toxicity in 104 Patients},
  author={U W E Wollina and K. St{\"a}nder and Ute Barta},
  journal={Clinical Rheumatology},
  year={2001},
  volume={20},
  pages={406-410}
}
Methotrexate (MTX) is an effective antipsoriatic agent but there are major concerns about its long-term toxicity, in particular to the liver. Reported frequencies and recommendations for monitoring patients on MTX vary considerably. The aim of this study was to analyse the frequency and severity of MTX-associated adverse drug reactions (ADR) in patients with psoriasis and psoriatic arthritis. A retrospective analysis was performed of 104 psoriasis and psoriatic arthritis patients (60 male, 44… CONTINUE READING

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