Toxicity and metabolism of methyl n-butyl ketone.


MEK (2-butanone) when combined with MBK (2-hexanone) markedly enhanced MBK neurotoxicity. MBK in rat plasma after exposure to MBK/MEK increased with time. Metabolites of MBK identified in blood and urine of rats and guinea pigs were 2-hexanol and 2,5-hexanedione. 


Cite this paper

@article{Abdelrahman1976ToxicityAM, title={Toxicity and metabolism of methyl n-butyl ketone.}, author={Mohamed Abdel-rahman and Lois Hetland and Daniel M. Couri}, journal={American Industrial Hygiene Association journal}, year={1976}, volume={37 2}, pages={95-102} }