Toxicity and carcinogenicity of potassium bromate--a new renal carcinogen.

  title={Toxicity and carcinogenicity of potassium bromate--a new renal carcinogen.},
  author={Yuji Kurokawa and Akihiko Maekawa and Masakazu Takahashi and Yuzo Hayashi},
  journal={Environmental Health Perspectives},
  pages={309 - 335}
Potassium bromate (KBrO3) is an oxidizing agent that has been used as a food additive, mainly in the bread-making process. Although adverse effects are not evident in animals fed bread-based diets made from flour treated with KBrO3, the agent is carcinogenic in rats and nephrotoxic in both man and experimental animals when given orally. It has been demonstrated that KBrO3 induces renal cell tumors, mesotheliomas of the peritoneum, and follicular cell tumors of the thyroid. In addition… CONTINUE READING
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