Toxicity after three-dimensional radiotherapy for prostate cancer with RTOG 9406 dose level IV.

@article{Michalski2004ToxicityAT,
  title={Toxicity after three-dimensional radiotherapy for prostate cancer with RTOG 9406 dose level IV.},
  author={Jeff Michael Michalski and Kathryn Winter and James A. Purdy and Carlos Alberto Perez and Janice K Ryu and Matthew B. Parliament and Richard K. Valicenti and Mack Roach and Howard Mark Sandler and Arnold M. Markoe and James D. Cox},
  journal={International journal of radiation oncology, biology, physics},
  year={2004},
  volume={58 3},
  pages={735-42}
}
PURPOSE This is the first report of the toxicity outcomes using dose level IV (74 Gy) on Radiation Therapy Oncology Group (RTOG) study 9406 for Stage T1-T2 prostate adenocarcinoma. METHODS AND MATERIALS A total of 262 patients were entered in this cooperative group, Phase I-II, dose-escalation trial of three-dimensional conformal radiotherapy for localized prostate carcinoma treated to a dose of 74 Gy (Level IV); 256 patients were analyzable for toxicity. A minimal dose of 2 Gy/fraction was… CONTINUE READING

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