Toxicity Studies of Genetically Modified Plants: A Review of the Published Literature

  title={Toxicity Studies of Genetically Modified Plants: A Review of the Published Literature},
  author={Josep L. Domingo},
  journal={Critical Reviews in Food Science and Nutrition},
  pages={721 - 733}
  • J. Domingo
  • Published 25 October 2007
  • Biology, Medicine
  • Critical Reviews in Food Science and Nutrition
According to the information reported by the WHO, the genetically modified (GM) products that are currently on the international market have all passed risk assessments conducted by national authorities. [] Key Method Studies about the safety of the potential use of potatoes, corn, soybeans, rice, cucumber, tomatoes, sweet pepper, peas, and canola plants for food and feed were included. The number of references was surprisingly limited. Moreover, most published studies were not performed by the biotechnology…

A literature review on the safety assessment of genetically modified plants.

Safety assessment of GM plants: An updated review of the scientific literature.

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  • Medicine
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 2016

What impact do genetically modified (GM) food have on our health

Some of the presented studies have been conducted by biotechnology companies responsible of commercializing these GM plants but without scientific evidence showing that GM food is safe, and the choice between traditional and non-conventional food remains to be decided exclusively by the consumers.

Risk Assessment of Genetically Modified Plants: A Review

In this review, the risk assessment of genetically modified plants is discussed in detail and a balance in the number of research groups, depending on their research, a variety of GM crops are varied as for traditional non-genetically modified plants.

GM crops and the rat digestive tract: a critical review.

Debate on GMOs Health Risks after Statistical Findings in Regulatory Tests

This study concluded that hepatorenal toxicities were possible, and that longer testing was necessary, and was criticized by the company developing the GMOs in question and the regulatory bodies.

Benefits and risks associated with genetically modified food products.

The presented study aims to systematize objective data on the potential benefits and risks resulting from the consumption of transgenic food, and particular attention was devoted to the short- and long-lasting undesirable effects.

Human Health Effects of Genetically Modified (GM) Plants: Risk and Perception

There was not sufficient published information concerning safety of GM foods in general, and GM crops/plants, in particular, 10 years ago, and a new and wide revision of the scientific literature on the potential adverse health/toxic effects of GM/transgenic plants was published.

Myths and Realities about Genetically Modified Food: A Risk-Benefit Analysis

The main purpose of this study is to review the impact of GM products on human, animal, and environmental health and report several benefits that result from their commercialization, such as economic, environmental, and health benefits for the general public.

Safety Assessment of Genetically Modified Feed: Is There Any Difference From Food?

The regulatory framework of GM crops intended for animal feed is reviewed using the available information on GM food as the baseline and the concentration of novel proteins in different plant tissues and level of exposure to GM feedstuff in the diet of target animals should be considered.



[Health risks of genetically modified foods: a literature review].

The main goal of this review has been to know which is the state-of-the art regarding to the potential adverse effects of GM foods.

The safety of genetically modified foods produced through biotechnology.

The SOT defines here its current consensus position on the safety of foods produced through biotechnology (genetic engineering), and supports the use of the substantial equivalence concept as part of the safety assessment of biotechnology-derived foods.

In vivo experiments on the safety evaluation of GM components of feeds and foods

The results of feeding experiments indicate that soyabean meal obtained from herbicide-tolerant lines and insect-resistant maize are substantially and nutritionally equivalent to their conventional lines.

In Vivo Studies on Possible Health Consequences of Genetically Modified Food and Feed—with Particular Regard to Ingredients Consisting of Genetically Modified Plant Materials

In this minireview the data made available in these published studies is discussed and the data consisting of genetically modified microorganisms or parts of animals/fish ingredients produced by/from genetically modified organisms is discussed.

Potential Adverse Health Effects of Genetically Modified Crops

  • A. Bakshi
  • Biology
    Journal of toxicology and environmental health. Part B, Critical reviews
  • 2003
The review of available literature indicates that the genetically modified crops available in the market that are intended for human consumption are generally safe; their consumption is not associated with serious health problems.

Multigeneration reproductive and developmental toxicity study of bar gene inserted into genetically modified potato on rats.

  • G. RheeD. Cho K. Choi
  • Biology, Medicine
    Journal of toxicology and environmental health. Part A
  • 2005
It is suggested that genetically modified crops have no adverse effects on the multigeneration reproductive-developmental ability and a science-based risk assessment is needed in order to use GM crops as a conventional foodstuff.

[Genetically modified foods. Advantages and human health risks].

One of the most important issue with which the mankind is confronting now is related to the quantitatively as well as qualitatively assurance of the food supply necessary for human species existence.

A 90-day safety study of genetically modified rice expressing Cry1Ab protein (Bacillus thuringiensis toxin) in Wistar rats.

  • Malene SchrøderM. Poulsen I. Knudsen
  • Biology, Medicine
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 2007

Are Genetically Modified Plants Useful and Safe?

  • J. Weil
  • Biology, Medicine
    IUBMB life
  • 2005
Possible risks for human health, the environment, or for the environment (such as the appearance of superweeds as a result from gene flow), should be carefully studied, and a science‐based assessment of benefits vs. risks should be made on a csae by case basis.