Toxic serum gentamicin levels after the use of gentamicin-loaded sponges in infected total hip arthroplasty.

Abstract

BACKGROUND At our clinic, total hip arthroplasties with an acute postoperative infection are treated with surgical debridement and application of several gentamicin-loaded sponges, each with an equivalent of 130 mg gentamicin. We studied the possible systemic effect of this local application of gentamicin. PATIENTS AND METHODS All 12 patients treated… (More)

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