Toxic epidermal necrolysis (Lyell's disease).

  title={Toxic epidermal necrolysis (Lyell's disease).},
  author={Mario Lissia and Pietro Mulas and Antonio Bulla and C. Rubino},
  journal={Burns : journal of the International Society for Burn Injuries},
  volume={36 2},
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe adverse drug reactions, characterized by a low incidence but high mortality, initially described as separate entities, but today considered variants of the same pathologic process and differing only for severity. The majority of cases appear to be related to idiosyncratic drug reactions. The drugs most commonly involved are: antibiotics such as sulfonamides, beta-lactam, tetracyclines and quinolones; anticonvulsants… CONTINUE READING