Corpus ID: 38932793

Toxic effects of formaldehyde on the nervous system

@inproceedings{Abdu2014ToxicEO,
  title={Toxic effects of formaldehyde on the nervous system},
  author={Hussein Abdu and Y. Kinfu and Asrat Agalu},
  year={2014}
}
Formaldehyde is a flammable, colourless gas with pungent odour and readily polymerized at ambient temperature. It is one of the major pollutants in indoor air. It is found in the environment as a result of natural processes and from man-made sources and it is widely used in industries and medical settings. Several symptoms might be manifested related to formaldehyde –exposure among which lethargy, decrease in motor activity, and loss of appetite is common. Formaldehyde resulted in minor… Expand

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References

SHOWING 1-10 OF 48 REFERENCES
The toxic effects of formaldehyde on the nervous system.
TLDR
The reviewed studies have indicated that FA has neurotoxic characteristics and systemic toxic effects, and it is hypothesized that inhalation of FA, during the early postnatal period, is linked to some neurological diseases that occur in adults. Expand
Zinc, copper and iron concentrations in cerebral cortex of male rats exposed to formaldehyde inhalation.
TLDR
It is concluded that subacute or subchronic exposure to formaldehyde may cause growth retardation and alter zinc, copper and iron levels in the cerebral cortex. Expand
Aldehydes: occurrence, carcinogenic potential, mechanism of action and risk assessment.
TLDR
Overall assessment of the cancer risk of aldehydes in the diet leads to the conclusion that formaldehyde, acrolein, citral and vanillin are no dietary risk factors, and that the opposite may be true for acetaldehyde, crotonaldehyde and furfural. Expand
Repeated Formaldehyde Effects in an Animal Model for Multiple Chemical Sensitivity
TLDR
Overall, the findings indicate that repeated low‐level chemical exposure produces behavioral changes that may be akin to those observed in individuals with MCS, such as greater sensitivity to chemicals manifest as increased anxiety upon chemical exposure and altered sleep and/or fatigue. Expand
Neurotoxic effects of acute and subacute formaldehyde exposures in mice.
TLDR
It is suggested that acute and subacute exposures of FA at low concentrations (such as 1.8 ppm) may increase the excitability of central nervous system (CNS) and reduce spontaneous locomotor activity (SLMA). Expand
Occupational asthma due to formaldehyde.
TLDR
A case of occupational asthma due to formaldehyde, which was confirmed by workplace challenge including working environmental assessments, and by formaldehyde inhalation challenge using a specially designed closed-circuit apparatus, was reported upon. Expand
Testicular zinc, copper and iron concentrations in male rats exposed to subacute and subchronic formaldehyde gas inhalation.
TLDR
It is concluded that subacute or subchronic exposure to formaldehyde have caused growth retardation and altered levels of trace elements, including copper, zinc and iron, in testicular tissue, and may induce further oxidative damage on testicular tissues leading to spermatozoal abnormalities. Expand
Caffeic acid phenethyl ester (CAPE) prevents formaldehyde-induced neuronal damage in hippocampus of rats
The aim of this study was to investigate the neurotoxicity of formaldehyde on hippocampus and the protective effects of caffeic acid phenethyl ester (CAPE) against these toxic effects. For thisExpand
The Effects of Inhaled Formaldehyde on Oxidant and Antioxidant Systems of Rat Cerebellum During the Postnatal Development Process
TLDR
The present findings suggest that inhalation of FA during the early postnatal period affects the oxidant and antioxidant systems and increases some free radicals in the rat cerebellum in a dose-related manner. Expand
Formaldehyde toxicity. Part II. Review of acute and chronic effects on health.
TLDR
The reactions of some international scientific bodies to the accumulated data are noted, and steps taken by a number of countries to control formaldehyde exposure in the workplace and other environments are discussed. Expand
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