Toxic Nodular Goiter and Cancer: A Compelling Case for Thyroidectomy

@article{Smith2012ToxicNG,
  title={Toxic Nodular Goiter and Cancer: A Compelling Case for Thyroidectomy},
  author={PhD J. Joshua Smith and Xi Chen and David F. Schneider and Ratnam Nookala MBBS and James T. Broome and Rebecca S. Sippel and Herbert C Chen and Carmen C. Sol{\'o}rzano},
  journal={Annals of Surgical Oncology},
  year={2012},
  volume={20},
  pages={1336-1340}
}
Recent American Thyroid Association guidelines call for thyroidectomy or 131I (Recommendation 31) in managing hyperthyroidism due to toxic nodular goiter (TNG). Concern for concomitant malignancy favors surgery. A 3 % thyroid cancer incidence in TNG patients has been reported, yet recent studies suggest this rate is underestimated. This multi-institutional study examined cancer incidence in TNG patients referred to surgery. Patients referred for thyroidectomy at three tertiary-care institutions… CONTINUE READING
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