Towards traceable size determination of extracellular vesicles

  title={Towards traceable size determination of extracellular vesicles},
  author={Z. Varga and Y. Yuana and A. Grootemaat and E. van der Pol and C. Gollwitzer and M. Krumrey and R. Nieuwland},
  journal={Journal of Extracellular Vesicles},
  • Z. Varga, Y. Yuana, +4 authors R. Nieuwland
  • Published 2014
  • Medicine, Materials Science
  • Journal of Extracellular Vesicles
  • Background Extracellular vesicles (EVs) have clinical importance due to their roles in a wide range of biological processes. The detection and characterization of EVs are challenging because of their small size, low refractive index, and heterogeneity. Methods In this manuscript, the size distribution of an erythrocyte-derived EV sample is determined using state-of-the-art techniques such as nanoparticle tracking analysis, resistive pulse sensing, and electron microscopy, and novel techniques… CONTINUE READING
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