Towards the introduction of the ‘Immunoscore’ in the classification of malignant tumours

  title={Towards the introduction of the ‘Immunoscore’ in the classification of malignant tumours},
  author={J{\'e}r{\^o}me Galon and Bernhard Mlecnik and Gabriela Bindea and Helen K. Angell and Anne Dunn Berger and Christine Lagorce and Alessandro Lugli and Inti Zlobec and Arndt Hartmann and Carlo Bifulco and Iris Nagtegaal and Richard Palmqvist and Giuseppe V Masucci and Gerardo Botti and Fabiana Tatangelo and Paolo Delrio and Michele Maio and Luigi Laghi and Fabio Grizzi and Martin Asslaber and Corrado D'Arrigo and Fernando Vidal-Vanaclocha and Eva Zavadova and Lotfi Chouchane and Pamela S Ohashi and Sara Hafezi-Bakhtiari and Bradly G. Wouters and Michael H. A. Roehrl and Linh Nguyen and Yutaka Kawakami and Shoichi Hazama and Kiyotaka Okuno and Shuji Ogino and Peter Gibbs and Paul M. Waring and Noriyuki Sato and Toshihiko Torigoe and Kyogo Itoh and Prabhudas Shankerbhai Patel and Shilin Nandubhai Shukla and Yi-Li Wang and Scott Kopetz and Frank A. Sinicrope and Viorel Scripcariu and Paolo Antonio Ascierto and Francesco M. Marincola and Bernard A Fox and Franck Pag{\`e}s},
  booktitle={The Journal of pathology},
The American Joint Committee on Cancer/Union Internationale Contre le Cancer (AJCC/UICC) TNM staging system provides the most reliable guidelines for the routine prognostication and treatment of colorectal carcinoma. This traditional tumour staging summarizes data on tumour burden (T), the presence of cancer cells in draining and regional lymph nodes (N) and evidence for distant metastases (M). However, it is now recognized that the clinical outcome can vary significantly among patients within… CONTINUE READING
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