Towards the establishment of a consensus real-time qPCR to monitor Trypanosoma cruzi parasitemia in patients with chronic Chagas disease cardiomyopathy: a substudy from the BENEFIT trial.

@article{Moreira2013TowardsTE,
  title={Towards the establishment of a consensus real-time qPCR to monitor Trypanosoma cruzi parasitemia in patients with chronic Chagas disease cardiomyopathy: a substudy from the BENEFIT trial.},
  author={Otac{\'i}lio da Cruz Moreira and Juan David Ram{\'i}rez and Elsa Vel{\'a}zquez and Myllena de F{\'a}tima Alheiros Dias Melo and Carolina Lima-Ferreira and Felipe Guhl and Sergio Sosa-Estani and Jos{\'e} Ant{\^o}nio Marin-Neto and Carlos A. Morillo and Constança Britto},
  journal={Acta tropica},
  year={2013},
  volume={125 1},
  pages={23-31}
}
Quantitative real-time PCR (qPCR) is an accurate method to quantify Trypanosoma cruzi DNA and can be used to follow-up parasitemia in Chagas disease (CD) patients undergoing chemotherapy. The Benznidazole Evaluation for Interrupting Trypanosomiasis (BENEFIT) study is an international, multicenter, randomized, double-blinded and placebo-controlled clinical trial to evaluate the efficacy of benznidazole (BZ) treatment in patients with chronic Chagas cardiomyopathy (CCC). One important question to… CONTINUE READING
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