Towards the Human Colorectal Cancer Microbiome

  title={Towards the Human Colorectal Cancer Microbiome},
  author={Julian R Marchesi and Bas E. Dutilh and Neil Hall and Wilbert H. M. Peters and Rian W. H. M. Roelofs and Annemarie Boleij and Harold 4 Tjalsma},
  booktitle={PloS one},
Multiple factors drive the progression from healthy mucosa towards sporadic colorectal carcinomas and accumulating evidence associates intestinal bacteria with disease initiation and progression. Therefore, the aim of this study was to provide a first high-resolution map of colonic dysbiosis that is associated with human colorectal cancer (CRC). To this purpose, the microbiomes colonizing colon tumor tissue and adjacent non-malignant mucosa were compared by deep rRNA sequencing. The results… CONTINUE READING
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